ACADVL Antikörper (N-Term)

Produktnummer ABIN2785735

Dieser Anti-ACADVL Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ACADVL in WB und IHC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen und Schwein. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ACADVL Antikörper (N-Term) (ABIN2785735)

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACADVL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ACADVL Antikörper

Bindungsspezifität: N-Term

Sequenz: RPYAGGAAQE SKSFAVGMFK GQLTTDQVFP YPSVLNEEQT QFLKELVEPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ACADVL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACADVL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 633 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACADVL Antikörper (ABIN2785735)

Yoon, Kang, Ryu, Poo: "Identification of tyrosine-nitrated proteins in HT22 hippocampal cells during glutamate-induced oxidative stress." in: Cell proliferation, Vol. 43, Issue 6, pp. 584-93, (2010) (PubMed).

Details zu ACADVL

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Andere Bezeichnung: ACADVL

Hintergrund: ACADVL is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in ACADVL protein reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy.The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: ACAD6, LCACD, VLCAD
Protein Interaction Partner: EEF2K, GPHN, RPSA, ATF2, CDH1, INTS9, ATP5L, UBC, SOCS3, ICT1, ACADVL,
Protein Size: 633

Molekulargewicht: 64 kDa

Gen-ID: 37

NCBI Accession: NM_001033859, NP_001029031

UniProt: P49748

Pathways: ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process